Search on: DNA-DEPENDENT DNA POLYMERASE III 
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Descriptor English:   DNA Polymerase III 
Descriptor Spanish:   ADN polimerasa III 
Descriptor Portuguese:   DNA Polimerase III 
Synonyms English:   DNA Dependent DNA Polymerase III
DNA Pol III
DNA Polymerase delta
DNA-Dependent DNA Polymerase III
Polymerase III, DNA
Polymerase delta, DNA  
Tree Number:   D08.811.913.696.445.308.300.235
Definition English:   A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms but may be present in higher organisms. Use also for a more complex form of DNA polymerase III designated as DNA polymerase III* or pol III* which is 15 times more active biologically than DNA polymerase I in the synthesis of DNA. This polymerase has both 3'-5' and 5'-3' exonuclease activities, is inhibited by sulfhydryl reagents, and has the same template-primer dependence as pol II. EC 2.7.7.7. 
History Note English:   91(77); for DNA POLYMERASE DELTA use DNA POLYMERASE III (NM) 1980-97 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   4325 
Unique Identifier:   D004258 

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